Please find attached the finals draw and finals structure for finals day of the 2015 National Touch League. To view, please click on the attachments below.Related Filesmodified_draw1-pdfmodified_draw_structure_and_format1-pdfRelated LinksModified Finals Draw
MONTREAL – One spring morning, Alfredo Rivas and his wife, who was seven months pregnant, grabbed the small bags containing their remaining belongings and headed north to Canada, a place they’d never seen.A week earlier, they’d decided to leave New York City amid worries the U.S. president’s promise to crack down on illegal immigration would put them at risk of being deported back to wartorn El Salvador.It’s a story that has recently become familiar to Canadians as the country has seen a rise in the number of refugee claimants crossing its southern borders — a phenomenon some have linked with rising anti-immigrant rhetoric and the election of U.S. President Donald Trump.Only, Rivas’ journey didn’t happen in recent months, and the president whose policies he was fleeing was Ronald Reagan, not Trump.While the scenes playing out at the Canadian border have garnered worldwide attention, northward migration is hardly unprecedented, says an author and historian who has studied the issue.“There’s a long history of people crossing the border fleeing U.S. policy and seeking refuge in Canada, whether you’re looking at African-Americans fleeing slavery in the 19th century, draft dodgers in the 1960s and ’70s, then refugees from Central America and other countries in the 1980s and ’90s,” John Rosinbum said in a phone interview.In November 1986, exactly 30 years prior to Trump’s election, Reagan signed the Immigration Reform Control Act, which stated that illegal immigrants who could not prove they had resided in the country for five years could be deported, and employers who hired them could be penalized.The move sent thousands of would-be refugees heading toward Canada, many of them originally from Central American countries such as Guatemala and El Salvador.This wave of arrivals caused Ottawa to dramatically shift positions in February 1987 and declare that asylum claimants would not be allowed to enter the country pending their hearing dates.The process essentially stranded hundreds of refugees, including Rivas and his wife, in communities along the Canada-U.S. border for weeks or months at a time, Rosinbum said.The small town of Plattsburgh, N.Y., pop. 20,000, unexpectedly found itself hosting an impromptu refugee camp for people originating from more than 50 countries.Without formal services in place, volunteers quickly jumped in to organize food, shelter and warm winter clothes for the refugees, according to former volunteer Margot Zeglis.“I think it was a surprise to everybody,” recalled Zeglis, who eventually co-ordinated the volunteer effort.“The Salvation Army was one of the first places they went but that was bursting at the seams, they would be sleeping under pews and filling the halllways with their small duffels of what their belongings were.”Eventually, she said, the volunteers became more sophisticated and formed partnerships with social services and various levels of government to organize better housing, food, counselling, translation services and entertainment for the guests.Despite the kindness of the volunteers, it was a stressful time, Rivas recalls.“They were small army beds, very small,” said Rivas, adding his wife’s stomach barely fit on one of the cots, which were lined up next to each other in rows.Rivas says he and his wife were allowed into Canada on April 6, 1987 — the same day his daughter was born.“They asked us (at the border) if we wanted the baby born in New York or Canada,” he said.While he chose New York, he said, his wife opted to give birth in Montreal — a decision he now concedes was the right one.Rivas, now a slim 58-year-old widower with two grown children, said many people who came up through Plattsburgh in 1987 are still friends.On a recent Sunday afternoon in Montreal, several of them met up for a backyard barbecue hosted by their friend Fredy Cruz, a fellow Salvadoran, to reminisce and eat plates of pupusas, or thick tortillas, filled with meat and cheese.Rivas’ friend, Nelson Gonzalez, who arrived at the lunch with Rivas, said he sees similarities between the run on the border in the late ’80s and the current situation under Trump.“It’s the same, always the same thing,” he said. “They’re scaring people to run from there. But it’s just a lot of talk.”Rivas, Cruz and Gonzalez, who all came to Canada in the same year, are now part of a group that helps raise funds to send money back to El Salvador.“We came here with nothing, just a small bag,” said Rivas, sitting at a picnic table in Cruz’s garage. “And now, we don’t have much, but we have something.”
The goal for the Fundraiser is set at $10,000 and they are close to reaching their goal.To view the GoFundMe CLICK HERE ROSE PRAIRIE, B.C. – Mid December the home of Jake and Brianne Dyksterhuis burnt down, causing them to lose the contents and their family vehicle.December 14th at 1 am the Dyksterhuis’s woke up to find their house was on fire, ‘there was only enough time to grab their daughter who was still sleeping in their bedroom and jump out the window in their night clothes’, states the GoFundMe page set up to help assist the family.As a young family with a nine-month-old daughter and another child due in the spring, a GoFundMe account was created to alleviate some of the financial burdens that come with losing everything.
Jose Mourinho is certain that Alexis Sanchez must start playing as soon as he arrives in the United States for Manchester United’s pre-season tour after missing their first gameThe Chile international was denied entry into the country after having an application for a US visa rejected.However, the issue has now been resolved and Mourinho is keen to get Sanchez out on to the field as soon as possible with Sunday’s next friendly against San Jose Earthquakes now just two days away.He told the club website: “I don’t even know if he is flying, if he is in Los Angeles or if he is in Manchester – I have no idea about it.“There will be no [Romelu] or [Marcus] Rashford, for sure, and we have to try with what we have.Maguire says United need to build on today’s win George Patchias – September 14, 2019 Harry Maguire wants his United teammates to build on the victory over Leicester City.During the summer, Harry Maguire was referred to as the ultimate…“It’s not about if he can play, it’s about when he has to. When Martial left the pitch, it was Mata [leading the attack]. When Mata went to the sides, it was a kid that trained with us for the first time this pre-season [Mason Greenwood].”The absence of forwards Romelu Lukaku and Marcus Rashford is having a telling effect on United with Mourinho not certain if they will be available for their opening Premier League game against Leicester City on August 10 with both stars currently away on holiday following their participation in the World Cup.“There’s no Lukaku or Rashford here and probably not even for the start of the Premier League, so it’s about when Alexis lands and when he lands, he has to play because he trained with us for five days before we departed to Los Angeles and we left one fitness coach behind with him to keep training with him. Of course, it’s individual training but when he arrives, he has to play,” said Mourinho.A Juan Mata goal spared United from defeat in their first preseason game against Mexican side Club America with the sides having to settle for a 1-1 draw at Phoenix.
The now Real Madrid goalkeeper won the award thanks to his fantastic performances while playing with Premier League club Chelsea last seasonBelgian goalkeeper Thibaut Courtois made tons of noise during the summer, after being transferred from English Premier League club Chelsea to Spanish La Liga side Real Madrid.The 26-years-old played with the Blues from 2011 to 2018, with a three-year-loan to Atletico Madrid.But during the summer he was transferred to Real Madrid, where he has just appeared in three occasions under the goal.Nonetheless, his great performances in North London made him deserve The Best FIFA Goalkeeper award today.He beat Hugo Lloris from Tottenham Hotspur and Kasper Schmeichel from Leicester City.Premier League Betting: Match-day 5 Stuart Heath – September 14, 2019 Going into the Premier League’s match-day five with a gap already beginning to form at the top of the league. We will take a…This is the first time the Belgian has won the award and might help him kick-start his career in the Spanish La Liga tournament.The Best FIFA Goalkeeper: 2017: Gianluigi Buffon – Juventus 2018: Thibaut Courtois – ChelseaCongratulations, Thibaut Courtois 👐Winner of #TheBest FIFA Goalkeeper 2018 🏆#FIFAFootballAwards pic.twitter.com/N1XVG9uYTf— #TheBest (@FIFAcom) September 24, 2018
The absence of Zlatan Ibrahimovic and his strong character was a big blow for Jose Mourinho at Manchester United, says football pundit Paul MersonAfter nearly two seasons, Ibrahimovic left Old Trafford in March for MLS side LA Galaxy amid struggles to regain full fitness from a knee ligament injury.Since the Swedish striker’s exit, Mourinho’s relationship with the likes of Paul Pogba hit a boiling point with United struggling in the process.The Portuguese coach was sacked on Tuesday after Sunday’s 3-1 defeat to Liverpool, which left United 19 points behind their rivals in sixth in the Premier League.And Merson believes Ibrahimovic’s departure left a huge void at United.“Zlatan Ibrahimovic was a big miss for Manchester United,” Merson told Sky Sports.“He was one of those players that Mourinho had in the dressing room where you didn’t need to keep on listening to the manager’s voice, and he would’ve picked players out.”The former Arsenal midfielder added that Ibrahimovic could have helped Mourinho in a similar manner to what Roy Keane did for Sir Alex Ferguson in the United dressing room.Pochettino admits Wanyama remains in his Spurs plans Manuel R. Medina – September 14, 2019 Kenyan international, Victor Wanyama, was the protagonist of a summer transfer saga, but in the end, he is set to stay at Tottenham Hotspur.“Zlatan would not have had what has happened in the last five or six weeks,” added Merson.“He would not have had some of the results, being 2-0 down at Southampton and being absolutely run ragged by Liverpool.“People will say they were trying, but let’s be honest, they got battered. It was embarrassing.“I think Zlatan would’ve gone in there and he would’ve started to dig players out and years ago you would’ve seen the same with Roy Keane and Sir Alex Ferguson.“Ferguson would’ve sat back and Keane would’ve come in and started to pick people out.“Peter Schmeichel would’ve been going mad along with the other experienced players. They would’ve then all calmed down and Sir Alex Ferguson would’ve had his say.”United legend Ole Gunnar Solskjaer has been confirmed as Mourinho’s replacement on an interim basis for the remainder of this season.
FIGC President Gabriele Gravina has maintained that the referee Paolo Silvio Mazzoleni who officiated the match between Napoli and Inter “could not interrupt” the due to racist abuse.He adds that he perfectly followed procedure and called for a statement which was made over the stadium speaker. It was stated that if racial abuse continues, the game will be temporarily suspended.“Mazzoleni could not interrupt the game. He perfectly followed procedure,” Federation chief Gravina told Rai Sport via Football Italia“Unfortunately, at times there are people who don’t know the procedures correctly.”Serie A Betting: Match-day 3 Stuart Heath – September 14, 2019 Considering there is a number of perfect starts so early in the Serie A season, as well as a few surprisingly not-so perfect ones….“The chief of security, in particular Questore Cardona, clearly stated that with five minutes left in the game, he could never have suspended play with the risk of creating a massacre.“Mazzoleni applied the procedure precisely the way it was planned. We will discuss with the Minister for the Interior to see if these procedures can be revised and simplified.“We can make it clearer that for example after three warnings in the stadium, the teams go back into the locker room, with the decision made by the security chief at the stadium.“In any case, there is already a system in place to apply very severe sanctions.”
Former Leicester City defender Robert Huth has announced his retirement from football after reports linking him with a move to Derby County.While responding to claims that he’s set to join Frank Lampard’s Derby County on an 18-month deal, Huth also revealed that has retired from playing football.Three-time Premier League winner 🏆@robert_huth has announced his retirement from football.More: https://t.co/4jMeUvdmLO pic.twitter.com/Q3l66opxGO— Sky Sports Premier League (@SkySportsPL) January 11, 2019Liverpool legend Nicol slams Harry Maguire’s Man United form Andrew Smyth – September 14, 2019 Steve Nicol believes Harry Maguire has made some “horrendous mistakes” recently, and has failed to find his best form since joining Manchester United.According to Sky Sports, the 34-year-old replied to the Twitter report saying: “This literally couldn’t be less true,” Huth said. “I’ve retired! (I just haven’t done an interview and cried about it).”Huth had quite a successful career playing only in England, as he represented Chelsea, Middlesbrough, Stoke, and Leicester.The defender came up through the Youth system at Chelsea and won two Premier League titles at Stamford Bridge during Jose Mourinho’s first spell in charge.He made 42 appearances for Chelsea and scored no goals, and left in 2016 to join Middlesbrough.The German center back would later Stoke City after three years at the Riverside Stadium and was part of Leicester’s squad that won the Premier League title against all odds in 2016.
The Spanish manager believes his team can still be saved this season, despite losing 2-1 against Chelsea and slipping into the bottom three of the Premier.After losing 2-1 against Chelsea in yesterday’s fixture of the English Premier League, Newcastle United fell into the 18th position.The Magpies have now only 4 wins, six draws, and 12 defeats so far in the 2018-2019 season.And are just 7 points ahead of the EPL’s last club Huddersfield Town.But Newcastle manager Rafa Benitez is still hopeful his team can be saved.Virgil van Dijk praises Roberto Firmino after Liverpool’s win Andrew Smyth – September 14, 2019 Virgil van Dijk hailed team-mate Roberto Firmino after coming off the bench to inspire Liverpool to a 3-1 comeback win against Newcastle United.“What I can see is that we have to stay calm,” he said to The Chronicle.“Next week will be massive against Cardiff but we still have to win more games than that.”“We have to do well in the rest of the season,” he explained.“I have confidence in the team and if we continue working like today we will have chances to get points against teams that will be closer to us.”
Publishing in Southern California is tough and always has been, Steve Churm says. Churm, the president of Churm Media, a city and regional publisher based in Orange County, remembers a FOLIO: report from 14 years ago. “In 1994 FOLIO: wrote, ‘The streets of Los Angeles would run red with blood if its magazine casualties were made of flesh instead of pulp,’” Churm said at the recent Niche Publishing Conference in Austin, Texas. “It’s more difficult today than it was 14 years ago to make a buck in the magazine industry in Southern California.”Churm should know. Two years ago, he was a $9.5 million company with seven magazines. Two years, two closed magazines and a topline that is $1 million less later, Churm is evaluating a strategy he embarked on to make his company brand centric and not just print centric. Churm, whose company publishes OC Metro, Southland Golf, OC Family and others, was the keynote speaker at the Niche Conference, a relatively new event geared to very small magazines. The event is run by Carl Landau, a publishing entrepreneur known, among other things, for a series of sales-training seminars called Camp Niche Jamboree. This year’s Niche Conference attracted 120 attendees and 17 sponsors. In Steve Churm, who launched his company in 1990, the conference had an engaging, candid keynote. “We embraced the idea that print and online work better together,” he said. “Our own print-centric thinking had gotten in our way.” He embraced that concept even though larger city and regional magazines, perhaps paradoxically, average less than 2 percent of their revenue from online sources, according to FOLIO:’s City and Regional Publishing Survey. To make it work, Churm said, he invested $350,000 to rebuild his Web sites—including an all-new content-management system—and all funded out of cashflow.The result? “We have not seen the payoff,” he said. “Not yet, anyway. We are entrepreneurs, and yes, we are going to fail. But you have to try.”A more promising initiative is the creation of Ripe Orange, an in-house ad agency designed to serve the company’s stable of 2,000 advertisers—many of whom are small and don’t have access to sophisticated creative services, Churm said. In 15 business days, Ripe Orange has booked $40,000 in business, Churm said. Churm offered eight lessons learned in the process of repositioning his company:1. Standalone repurposed content isn’t compelling to anyone. Write and present content for the medium it is intended. 2. Take advantage of being online. There are clever ways to alert readers of other resources.3. Provoke readers, but don’t annoy them online.4. Quality content rules. Provide value and people will come back.5. Every person working on your Web sites should get used to being overworked indefinitely.6. Document, document, document. Programmers and producers are not going to stay with you for long. When they leave, if you haven’t documented, you have a problem.7. Useful is better than cool. Be respectful of readers’ time limitations.8. Fear of failure—you can’t be afraid of making a mistake. “Lee Iacocca said in his book that his regret was that he didn’t fail earlier and more often in his career,” Churm said. “You’ve got to put yourself out there.”
NETWORK ERRORCannot Contact ServerRELOAD YOUR SCREEN OR TRY SELECTING A DIFFERENT VIDEO Oct 9, 2017 – 12:11 pm Russell Thompkins Jr. On Thom Bell’s Impact Thom Bell’s “Major Influence” On The Stylistics thom-bells-major-influence-stylistics Thom Bell’s “Major Influence” On The Stylistics Facebook Email This is something Russell Thompkins Jr. knows intimately as a member of the Philly soul group the Stylistics, for whom Bell co-wrote and produced several hits, including “I’m Stone In Love With You,” “Stop, Look, Listen (To Your Heart)” and “You Are Everything.””He was the major influence of my career,” says Thompkins. “When I first went in with Tommy, I think I was 19 or 20 years old. That’s when I first started learning my craft. And from the things that I learned from doing the sessions with him, it’s lasted me my whole career.”Now, Thompkins will have a chance to honor Bell, a 2017 Recording Academy Trustees Award recipient, for his contributions to the music industry during the Academy’s “GRAMMY Salute To Music Legends” two-hour TV special in recognition of this year’s class of Special Merit Awards recipients.Thompkins will perform a rendition of “You Make Me Feel Brand New” in Bell’s honor, one of the biggest songs Bell did with the Stylistics. But Thompkins’ favorite Bell tune?”My favorite song of Thom Bell’s in ‘Betcha By Golly Wow,'” says Thompkins. “It’s the song in my show that I never get tired of performing. It’s a wonderful song. I think out of the Stylistics’ songs, it’s the most recorded and done by other artists.”Tune in to “GRAMMY Salute To Music Legends” on PBS on Oct. 13 at 9 p.m. on PBS. In addition to Bell, honorees will include Lifetime Achievement Award recipients Sly Stone, Charley Pride and Shirley Caesar. Other artists scheduled to pay tribute to the honorees include Andra Day, Dwight Yoakam and Kirk Franklin.”GRAMMY Salute To Music Legends”: Performers And Full Set ListRead more News Twitter Ahead of the “GRAMMY Salute To Music Legends” TV special, take a look at how producer/label exec Thom Bell impacted the Stylistics and the sound of the Stylistics and Philly soulRenée FabianGRAMMYs Oct 9, 2017 – 12:12 pm There would have been no classic sound of Philadelphia soul in the 1970s if it weren’t for producer/record label executive Thom Bell.
Amy Jackson, British fiancee George PanayiotouInstagram2.0 actress Amy Jackson is currently in her third trimester and she is enjoying every phase of her pregnancy with her British fiancee George Panayiotou. The couple are currrently holidaying in Europe and Amy is leaving no stone unturned in making every moment a memorable one.The soon-to-be mother is known for pulling off every kind of cloth on body and has been setting a new precedent with her materity outfits for pregnant women. Sharing a few pictures on Instagram, Amy was seen flaunting her baby bump while soaking in the sun in a yellow bikini and needless to say that she was beaming with her pregnancy glow. In another picture, Amy and George shared an intimate moment wherein George was seen holding on the baby bump.Being a fitness freak, Amy Jackson has been working out rigorously. A few days ago, she shared a picture wherein she spoke about her pregnancy cravings. And if you are following her on Instagram, you wouldn’t be able take your eyes off her breathtaking pictures.After announcing her pregnancy on Mother’s Day, Amy and George got engaged in an intimate ceremony in London on May 5 and had been sharing some of their lovey-dovey moments on social media which you just can’t resist. Amy JacksonInstagram Amy Jackson flaunts her baby bump while soaking in the sun during her Europe trip with British fiancee George PanayiotouInstagram
Close Chanda Kochhar, Managing Director and Chief Executive Officer of ICICI BankReutersAs the Videocon dirty loan investigation moves into another gear, the ICICI Bank board of directors has finally decided to remove tainted CEO and Managing Director Chanda Kochhar. The latest reports suggest Sandeep Bakhshi, the head of the bank’s insurance division, will become the next CEO.The two momentous decisions that will change the course for India’s second largest lender under allegations of partisan loan sanctions, are likely to be announced today after a crucial board meeting, the Economic Times reported.Kochhar, who has been in sharp focus over the loans ICICI sanctioned to the Videocon Group, is currently on leave but has more than year in her as CEO under the contract.The ET report said the bank has informed the Insurance Regulatory and Development Authority (IRDA) that Bakhshi may be moved to a different role at India’s largest private bank by assets. IBTimes VideoRelated VideosMore videos Play VideoPauseMute0:01/0:49Loaded: 0%0:01Progress: 0%Stream TypeLIVE-0:48?Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedSubtitlessubtitles settings, opens subtitles settings dialogsubtitles off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. COPY LINKAD Loading … The board meeting on Monday will also finalise the terms of the appointment of Justice BN Srikrishna as the committee to investigate the allegations of conflict of interest by Kochhar.Kochhar has battled unsavoury attention ever since a whistleblower complaint linked her to irregularities in the sanctioning of a multi-crore loan to the Videocon group. The whistleblower alleged that ICICI Bank gave a Rs 3,250 crore loan to the Videocon Industries in 2012 under Kochhar’s watch.Independent probeThe complaint said that a few months before that loan was sanctioned, Videocon chairman Venugopal Dhoot had lent a whopping Rs 66 core to Deepak Kochhar, the CEO’s husband.Though the bank defender Kochhar, it yielded to investor and regulatory pressures and announced an independent probe into charges against Kochhar earlier this month and asked her to go on indefinite leave.Apart from the whistleblower complaint, investor Arvind Gupta had also alleged in 2016 that the loans to Videocon were a clear case of conflict of interest. He had said that the funding of a company called NuPower jointly by Dhoot and Deepak Kochhar pointed to the possibility of there being a quid pro quo behind the sanction of loans. In March this year, the CBI launched a probe into the connection between Videocon group and Kochhar’s husband. The bank had said last week chief executive Kochhar had received a notice from markets regulator Securities and Exchange Board of India seeking responses over alleged non-compliance. BIGGEST BANK FRAUDS IN 2018
This picture shows flooded streets in Regent near Freetown, on 14 August, 2017. Photo: AFPAt least 312 people were killed and more than 2,000 left homeless on Monday when heavy flooding hit Sierra Leone’s capital of Freetown, leaving morgues overflowing and residents desperately searching for loved ones.An AFP journalist at the scene saw bodies being carried away and houses submerged in two areas of the city, where roads turned into churning rivers of mud and corpses were washed up on the streets.Red Cross spokesman Patrick Massaquoi told AFP the death toll was 312 but could rise further as his team continued to survey disaster areas in Freetown and tally the number of dead.Mohamed Sinneh, a morgue technician at Freetown’s Connaught Hospital, said 180 bodies had been received so far at his facility alone, many of them children, leaving no space to lay what he described as the “overwhelming number of dead”.Many more bodies were taken to private morgues, Sinneh said.Images obtained by AFP showed a ferocious churning of dark orange mud coursing down a steep street in the capital, while videos posted by local residents showed people waist and chest deep in water trying to traverse the road.Fatmata Sesay, who lives on the hilltop area of Juba, said she, her three children and husband were awoken at 4:30 am by rain beating down on the mud house they occupy, which was by then submerged by water.She managed to escape by climbing onto the roof.“We have lost everything and we do not have a place to sleep,” she told AFP.Piles of corpses -Local media reports said a section of a hill in the Regent area of the city had partially collapsed, exacerbating the disaster.Other images showed battered corpses piled on top of each other, as residents struggled to cope with the destruction.Meanwhile disaster management official Candy Rogers said that “over 2,000 people are homeless,” hinting at the huge humanitarian effort that will be required to deal with the fallout of the flooding in one of Africa’s poorest nations.Freetown, an overcrowded coastal city of 1.2 million, is hit each year by flooding during several months of rain that destroys makeshift settlements and raises the risk of waterborne diseases such as cholera.Flooding in the capital in 2015 killed 10 people and left thousands homeless.Sierra Leone was one of the west African nations hit by an outbreak of the Ebola virus in 2014 that left more than 4,000 people dead in the country, and it has struggled to revive its economy since the crisis.About 60 percent of people in Sierra Leone live below the national poverty line, according to the United Nations Development Programme.
What kinds of problems women can have after giving birthIt’s still rare for a woman to die during or after childbirth; however, a lot of these deaths are unnecessary and preventable.“The problem is that it’s so rare that people are still just realizing that this is still a thing that happens in the United States,” Evans said.These deaths happen quickly after birth, within a matter of hours, days or weeks. Hemorrhaging and issues with C-sections are more immediate causes of deaths, but in the weeks after a woman gives birth, blood clots, strokes and postpartum preeclampsia can threaten her life.“When you’re about to take care of a newborn, you might not even be thinking about your own health and your own safety,” Evans said. “You’re thinking about keeping your newborn alive. You’re thinking about, ‘What does he or she need as they come into this world?’”Evans said discussions about postpartum depression are improving, but doctors are still having trouble educating their patients about stroke, heart attacks and other serious conditions after childbirth.On maternal mortality and black womenThe state’s task force on maternal mortality has found that black women are the most at risk of dying after childbirth or having complications, Evans said.“We really can’t talk about black women and black maternal health unless we’re talking about systemic racism in the health care system,” she said. “You have women who do not feel like they can talk to their doctors. You have unconscious bias against black women when they’re trying to ask questions, or perceptions about ‘if they’ll follow their doctor’s orders when it comes to their health plans.’”This is @SerenaWilliams like you’ve never seen her before. Our February cover star opens up about her recent health scare, the first couple months of motherhood, and how she’s not slowing down anytime soon. https://t.co/bhT541QpLD— Vogue Magazine (@voguemagazine) January 11, 2018All of that factors into how black women are welcomed into the health care system, Evans said. She points to Serena Williams’ recent disclosure of her own pregnancy complications and fighting her doctors to get the care she needed.Evans said Williams’ experience will help people think about how they perceive black women and black mothers and mothers in general in their postpartum period.“Mothers after giving birth know their bodies better than anybody else,” Evans said. Share GABRIEL CRISTOVER PEREZ / KUTIn Texas, mothers are dying — and lawmakers and public health officials are trying to figure out why.Maternal mortality is defined when a mother dies from pregnancy-related complications while pregnant or within 42 days of giving birth, according to the Texas Tribune. Nationwide, the rate rose by 27 percent between 2000 and 2014, according to a 2016 study published in “Obstetrics and Gynecology.”In Texas, the maternal mortality rate had doubled between 2010 and 2012, shocking researchers. The state’s mortality rate hit its highest level in 2012 when 148 women died. As the Texas Tribune reported: “A new study says the rates from 2011 to 2015 were likely inflated because of misreporting on death certificates. The Texas Department of State Health Services has begun using a new methodology for 2012 onward, which it says produces a more accurate rate.”On KERA’s “Think,” Marissa Evans, a reporter with the Tribune, provided context to the numbers, which show among other things that black women are disproportionately at risk.Interview highlightsWhy it’s hard to quantify maternal mortalityThe definitions behind maternal mortality differ at the state and federal level.“When you have these two very important agencies, in our case, the Texas Department of State Health Services and the federal Centers for Disease Control [and Prevention], saying ‘We’re counting it in these different ways and we have these different numbers to show for it.’ That’s where we come into having a problem,” Evans said.But everyone that Evans spoke to in her reporting agrees that regardless of what the numbers are, they are rising in Texas.“No matter how you look at the definitions, people still need to be paying attention to this issue and we still need to figure out what we can do to protect mothers as they prepare for childbirth,” she said.Texas, however, is not the only state struggling with maternal mortality. Mississippi also has a high rate. And California once had a high rate, but is starting to lower it.The rate is rising across the country, but Texas is still considered a “top 10 place” for the issue.
Listen X To embed this piece of audio in your site, please use this code: TABC has been doing what it calls “minor stings.” During those operations, agents observe while an underaged person attempts to buy alcohol. They’ve been doing those stings along travel corridors near college campuses. Other operations have taken place on South Padre Island and Austin’s SXSW festival.When a violation occurs, TABC’s Chris Porter said it may be a situation where the retailer just needs additional training.“A lot of times what we see is perhaps a clerk is too busy to do the proper checks,” explained Porter. “Or in some cases, especially for bars and nightclubs, perhaps a bartender is relying upon someone outside the door checking ID’s as they come in.”Porter said it’s not their goal to put retailers out of business. “What we want to do is make sure they have the tools they need to prevent these kind of sales.”TABC says about 95% of the businesses they check are in compliance. They’ve done close to 120 stings over the past week here in the Houston region and Porter said they’ve only found a handful of violations.TABC Deputy Executive Director for Enforcement Robert Saenz said they want to ensure that any alcohol sold during the Spring Break season is done so safely and legally. They plan to continue their efforts heading into the summer months.“TABC will continue to serve as a resource for retailers who have questions about the law and its impact on their day-to-day operations,” added Saenz. 00:00 /00:46 Share
Citation: Host cell-entry mode of African henipavirus could be its Achilles heel (2015, April 14) retrieved 18 August 2019 from https://phys.org/news/2015-04-host-cell-entry-mode-african-henipavirus.html (Phys.org)—The recognition of a suite of African henipaviruses (HNVs), which are related to pathogenic Hendra and Nipah viruses, is a wake-up call to medical organizations worldwide. The initial symptoms of henipavirus infection—fever and headache followed by rapid-onset encephalitis—have likely resulted in misdiagnosis by medical workers as malaria-associated encephalitis, and fatalities from infection approach 90 percent. As a result of the symptomatic commonalities between henipaviruses and other paramyxoviruses, researchers are now reassessing the spread of HNVs. Crystal structure of GhV-G in complex with ephrinB2. The six-bladed β-propeller of GhV-G is shown as a rainbow ramped from blue (N terminus) to red (C terminus). The Greek-key fold of ephrinB2 is shown as a gray cartoon. Asparagine-linked N-acetylglucosamine moieties are shown as pink sticks. Credit: (c) PNAS 2015, doi:10.1073/pnas.1501690112 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Mechanism found for development of protective HIV antibodies More information: “Molecular recognition of human ephrinB2 cell surface receptor by an emergent African henipavirus.” PNAS 2015 ; published ahead of print March 30, 2015, DOI: 10.1073/pnas.1501690112AbstractThe discovery of African henipaviruses (HNVs) related to pathogenic Hendra virus (HeV) and Nipah virus (NiV) from Southeast Asia and Australia presents an open-ended health risk. Cell receptor use by emerging African HNVs at the stage of host-cell entry is a key parameter when considering the potential for spillover and infection of human populations. The attachment glycoprotein from a Ghanaian bat isolate (GhV-G) exhibits <30% sequence identity with Asiatic NiV-G/HeV-G. Here, through functional and structural analysis of GhV-G, we show how this African HNV targets the same human cell-surface receptor (ephrinB2) as the Asiatic HNVs. We first characterized this virus−receptor interaction crystallographically. Compared with extant HNV-G–ephrinB2 structures, there was significant structural variation in the six-bladed β-propeller scaffold of the GhV-G receptor-binding domain, but not the Greek key fold of the bound ephrinB2. Analysis revealed a surprisingly conserved mode of ephrinB2 interaction that reflects an ongoing evolutionary constraint among geographically distal and phylogenetically divergent HNVs to maintain the functionality of ephrinB2 recognition during virus–host entry. Interestingly, unlike NiV-G/HeV-G, we could not detect binding of GhV-G to ephrinB3. Comparative structure–function analysis further revealed several distinguishing features of HNV-G function: a secondary ephrinB2 interaction site that contributes to more efficient ephrinB2-mediated entry in NiV-G relative to GhV-G and cognate residues at the very C terminus of GhV-G (absent in Asiatic HNV-Gs) that are vital for efficient receptor-induced fusion, but not receptor binding per se. These data provide molecular-level details for evaluating the likelihood of African HNVs to spill over into human populations. Explore further Journal information: Proceedings of the National Academy of Sciences © 2015 Phys.org Since the 1990s, more than 20 henipaviruses have been detected throughout Africa, Asia, Australia and Central America. The virus resides in populations of Old World fruit bats and its introduction to humans is believed to be through animal intermediaries such as pigs, or through the slaughter of the bats themselves for meat. HNVs are extremely pathogenic, and have been designated as high-priority agents that require handling under stringent biosafety conditions.Due to the potential for spillover from animal to human populations, researchers are focusing on the molecular-level structure of the viruses in order to determine their host-cell entry activities. A group of U.S.- and U.K.-based researchers have recently published a paper in the Proceedings of the National Academy of Sciences that studies a human cell surface receptor recognized by an emergent African hepinavirus strain called GhV, derived from a Ghanian fruit bat. They found that despite targeting a particular binding scaffold that exists across a range of HNVs, the molecular differences between these viruses prevented cross-reaction of antibodies, inhibiting development of a vaccination strategy.Currently the only African HNV for which envelope sequence information is available, GhV is related to other highly contagious HNVs, and the researchers find that it displays an HNV-G β-propeller binding scaffold similar to that in Asiatic HNVs. Despite structural differences, these structures are capable of of accommodating nearly identical primary ephrinB2-binding modes at the surfaces of host cells. The researchers note that bat and human cell-surface ephrinB2 sites are quite similar and likely maintain similar modes of binding, and that cross-infections are therefore likely.They write, “… the apparent structural plasticity and low level of sequence conservation on the HNV-G receptor-binding β-propeller scaffold are likely to prove an obstacle in the rational design of vaccines that produce broadly neutralizing antibodies to the ever-expanding spectrum of HNVs and HNLVs.”The virus-receptor interaction was confirmed via crystallography, and the researchers noted significant structural differences with previously documented HNV-G-ephrinB2 structures, but not in the key fold of the bound ephrinB2. They conclude that this conserved mode of ephrinB2 interaction represents an evolutionary constraint across divergent HNVs.Through structure-based phylogenic analysis, the researchers found that GhV-G and its cognate in Asiatic NiV likely evolved separately, after the viruses bifurcated from a common ephrin-binding HNV ancestor. They speculate that the ephrin-2 binding site represents a constraint of evolution that has conserved ephrinB2 binding by HNVs, a potential Achilles heel that could be exploited in vaccine research. The researchers introduced GhV to antibodies against NiV, finding that they did not cross-react with the GhV-G binding scaffold. Those antibodies also failed to neutralize CedV, a distantly related HNV. Despite a failure to find these cross-reactions, the researchers note that all of the studied HNVs mediate ephrinB2-dependent host-cell entry, and suggest that prime-boost vaccination is a possible strategy for eliciting broadly neutralizing antibodies that can target the ephrinB2-binding sites across a diverse HNVs.
A new report from video ad specialist Smartclips has found that 70% of people with internet connected TVs use the online functions.The survey of 1,536 14-49 year-olds found that 56% own a device that makes it possible to use the internet via a TV screen, whether directly via a smart TV, or via a connected TV device such as a Blu-ray player or a gaming console.Irrespective of the device used, 26% of respondents said they nearly always use the internet whilst watching the TV, with a further 37% saying they use the internet frequently whilst watching the TV. Two-thirds of tablet owners said they use the internet frequently whilst watching TV.When asked what was interesting about connected TV, 84% stated the non-linear viewing of TV and movies. Less than half chose looking for products from TV or online adverts.